Description

Cyclopentaneacetic Acid, -α--Amino-1-Mercapto-, (-α-R)- (9Ci) is a high-purity, chiral building block featuring a unique cyclopentane backbone integrated with amino and mercapto functional groups. This compound is of significant value for the development of novel pharmaceuticals and bioactive molecules, particularly in the synthesis of peptidomimetics and enzyme inhibitors. It is primarily sought by research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in oncology and metabolic disease research.
• Peptidomimetic Synthesis: Used to construct non-peptide scaffolds that mimic the structure and function of natural peptides, enhancing metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis or for metal chelation studies.
• Bioconjugation Chemistry: The mercapto (-SH) group enables site-specific conjugation to proteins, antibodies, or other biomolecules for drug delivery systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce complex, functionalized cyclopentane motifs into target molecules.

Basic Information

Product Name	Cyclopentaneacetic Acid, -α--Amino-1-Mercapto-, (-α-R)- (9Ci)
CAS No.	255052-59-6
Molecular Formula	C7H13NO2S
Molecular Weight	175.25 g/mol
Synonyms	(R)-2-Amino-2-(cyclopentyl)ethanethioic acid; (αR)-α-Amino-1-mercaptocyclopentaneacetic acid; (R)-2-Amino-2-cyclopentyl-2-sulfanylacetic acid; 2-Amino-2-cyclopentylethanethioic acid, (R)-; 255052-59-6; Cyclopentaneacetic acid, α-amino-1-mercapto-, (αR)-; (R)-2-Amino-2-cyclopentyl-2-mercaptoacetic acid
EINECS	Contact for details

Quality Control

Our Cyclopentaneacetic Acid, -α--Amino-1-Mercapto-, (-α-R)- (9Ci) is manufactured under strict quality control protocols to ensure high chemical and chiral purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The material is easily oxidized; prolonged exposure to air should be avoided. Keep the container in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.