Description

3-(2-Methoxycarbonyl-Ethyl)-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in regulated synthesis pathways. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially those containing indole or tryptamine cores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its functionalized indole structure.
• Organic Synthesis: Serves as a versatile precursor for introducing protected carboxylic acid and ester functionalities in multi-step synthetic routes.
• Peptidomimetics & Bioconjugation: Employed in the design and synthesis of peptide analogs and for creating bioconjugates via its reactive ester group.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	3-(2-Methoxycarbonyl-Ethyl)-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	253605-13-9
Molecular Formula	C17H21NO4
Molecular Weight	303.35 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-(2-methoxy-2-oxoethyl)indole; 1-Boc-3-(2-methoxy-2-oxoethyl)indole; tert-Butyl 3-(2-methoxy-2-oxoethyl)-1H-indole-1-carboxylate; 3-(2-Carbomethoxyethyl)-1H-indole-1-carboxylic acid tert-butyl ester; 3-(2-Methoxycarbonylethyl)indole-1-carboxylic acid tert-butyl ester; 1H-Indole-1-carboxylic acid, 3-(2-methoxy-2-oxoethyl)-, 1,1-dimethylethyl ester; BOC-3-(2-COOMe-ethyl)indole
EINECS	Contact for details

Quality Control

Our 3-(2-Methoxycarbonyl-Ethyl)-Indole-1-Carboxylic Acid tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance in GMP-aligned synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.