Description

Methyl 5-(tert-Butyl)-3-(Chloromethyl)Thiophene-2-Carboxylate CAS NO 252914-61-7 is a high-value, multi-functional thiophene derivative characterized by its reactive chloromethyl group and ester functionality. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Monomer or functional additive in the production of conductive polymers, organic semiconductors, and specialty coatings.
• Organic Synthesis: Versatile reagent for introducing the thiophene moiety and for further functionalization via nucleophilic substitution of the chloromethyl group.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Research & Development: Essential compound for medicinal chemistry research and process development in fine chemical manufacturing.

Basic Information

Item	Detail
Product Name	Methyl 5-(tert-Butyl)-3-(Chloromethyl)Thiophene-2-Carboxylate
CAS No.	252914-61-7
Molecular Formula	C11H15ClO2S
Molecular Weight	246.75 g/mol
Synonyms	Methyl 5-tert-butyl-3-(chloromethyl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 5-(1,1-dimethylethyl)-3-(chloromethyl)-, methyl ester; 3-(Chloromethyl)-5-tert-butylthiophene-2-carboxylic acid methyl ester; 5-tert-Butyl-3-chloromethylthiophene-2-carboxylic acid methyl ester; MBCT; tert-Butyl Chloromethyl Thiophene Carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 5-(tert-Butyl)-3-(Chloromethyl)Thiophene-2-Carboxylate adheres to stringent in-process controls and final batch testing to ensure high purity and consistent quality. Every lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The compound is stable under recommended storage conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.