Description

8-Bromo-5-Nitro-Isoquinoline is a high-purity, heterocyclic aromatic compound serving as a critical building block in advanced organic synthesis. Its unique halogenated and nitrated isoquinoline structure makes it an invaluable intermediate for the development of complex molecules. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogen and nitro functional groups for structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers, ligands for metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to the reactive bromo and nitro substituents.
• Dye & Pigment Industry: Acts as a starting material for synthesizing complex heterocyclic dyes and colorants.
• Academic & R&D: A valuable reagent for methodological development and exploratory research in organic and medicinal chemistry laboratories worldwide.

Basic Information

Product Name	8-Bromo-5-Nitro-Isoquinoline
CAS No.	252861-41-9
Molecular Formula	C9H5BrN2O2
Molecular Weight	253.06 g/mol
Synonyms	8-Bromo-5-nitroisoquinoline; Isoquinoline, 8-bromo-5-nitro-; 5-Nitro-8-bromoisoquinoline; 252861-41-9; 8-Br-5-NO2-IQ
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-5-Nitro-Isoquinoline is manufactured and tested under strict quality management protocols to ensure consistency and purity for your critical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere if prolonged exposure is anticipated.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.