Description

6-Fluoro-2-Methyl-3-(4-Piperidine)-1H-Indole is a high-purity, heterocyclic organic compound featuring a fused indole and piperidine structure with a fluorine substituent. This molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate for research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its privileged indole-piperidine scaffold.
• Biochemical Tool Compound: Serves as a precursor or reference standard in the development of probes for biological target identification and validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for organic synthesis methodology development and heterocyclic chemistry studies.

Basic Information

Item	Detail
Product Name	6-Fluoro-2-Methyl-3-(4-Piperidine)-1H-Indole
CAS No.	252354-45-3
Molecular Formula	C14H17FN2
Molecular Weight	232.30 g/mol
Synonyms	6-Fluoro-2-methyl-3-(piperidin-4-yl)-1H-indole; 3-(4-Piperidinyl)-6-fluoro-2-methyl-1H-indole; 6-Fluoro-2-methyl-3-piperidin-4-yl-1H-indole; 252354-45-3; 6-Fluoro-2-methyl-3-(4-piperidyl)indole; 4-(6-Fluoro-2-methyl-1H-indol-3-yl)piperidine
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Methyl-3-(4-Piperidine)-1H-Indole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.