Description

11-(p-Tolylamino)-7,8,9,10-Tetrahydrobenzo[4,5]Imidazo[1,2-B]Isoquinoline-6-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in the research and development of novel therapeutic agents, particularly due to its potential as a key building block for active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in QC laboratories.
• Academic & Industrial R&D: Utilized in research programs focused on developing new heterocyclic compounds with potential biological activity.
• Fine Chemical Production: Integrated into multi-step synthesis processes for the manufacture of complex, high-value specialty chemicals.

Basic Information

Product Name	11-(p-Tolylamino)-7,8,9,10-Tetrahydrobenzo[4,5]Imidazo[1,2-B]Isoquinoline-6-Carbonitrile
CAS No.	251983-44-5
Molecular Formula	C25H20N4
Molecular Weight	376.46 g/mol
Synonyms	11-[(4-Methylphenyl)amino]-7,8,9,10-tetrahydrobenzo[4,5]imidazo[1,2-b]isoquinoline-6-carbonitrile; 11-(4-Methylanilino)-7,8,9,10-tetrahydrobenzo[4,5]imidazo[1,2-b]isoquinoline-6-carbonitrile; Benzo[4,5]imidazo[1,2-b]isoquinoline-6-carbonitrile, 7,8,9,10-tetrahydro-11-[(4-methylphenyl)amino]-; 11-(p-Tolylamino)-7,8,9,10-tetrahydrobenzo[4,5]imidazo[1,2-b]isoquinoline-6-carbonitrile
EINECS	Contact for details

Quality Control

Our 11-(p-Tolylamino)-7,8,9,10-Tetrahydrobenzo[4,5]Imidazo[1,2-B]Isoquinoline-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.