Description

1,3-Benzenediol, 5-[(1R)-1-Hydroxy-2-[(2-Methylpropyl)Amino]Ethyl]- (9Ci) is a specialized chiral organic compound of significant interest in advanced pharmaceutical synthesis and fine chemical research. Its molecular structure, featuring a resorcinol core linked to an amino alcohol side chain, makes it a valuable key intermediate for developing active pharmaceutical ingredients (APIs) with targeted biological activity. This high-purity compound is essential for research and development chemists, process scale-up specialists, and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality building blocks for complex molecule construction.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel β-adrenergic receptor agonists or related therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for creating new drug candidates targeting respiratory, cardiovascular, or metabolic disorders.
• Asymmetric Synthesis: Employed in chiral synthesis routes due to its defined (R)-configuration, enabling the production of enantiomerically pure compounds.
• Biochemical Research: Acts as a standard or probe molecule in studies investigating adrenergic receptor interactions and signal transduction pathways.
• Fine Chemical Manufacturing: Utilized in the production of complex, high-value specialty chemicals for various industrial and research applications.
• Process Chemistry & Scale-Up: Provides a defined starting material for optimizing synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	1,3-Benzenediol, 5-[(1R)-1-Hydroxy-2-[(2-Methylpropyl)Amino]Ethyl]- (9Ci)
CAS No.	251907-03-6
Molecular Formula	C12H19NO3
Molecular Weight	225.28 g/mol
Synonyms	(R)-5-(1-Hydroxy-2-(isobutylamino)ethyl)benzene-1,3-diol; (R)-3,5-Dihydroxy-α-[(isobutylamino)methyl]benzyl alcohol; (R)-Isoetharine Intermediate; (R)-α-[(Isobutylamino)methyl]protocatechuyl alcohol; 1,3-Benzenediol, 5-[(1R)-1-hydroxy-2-[(2-methylpropyl)amino]ethyl]-; (R)-1-(3,5-Dihydroxyphenyl)-2-(isobutylamino)ethanol; Isoetharine (R)-enantiomer precursor; 4-[(1R)-1-Hydroxy-2-(isobutylamino)ethyl]benzene-1,3-diol
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, and chiral analysis to ensure identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications. We support development and cGMP manufacturing needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.