Description

(R)-3-((1-Methylpyrrolidin-2-Yl)Methyl)-1H-Indol-4-Ol is a chiral indole derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated pharmaceutical intermediate and a key building block for the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors, particularly those focused on neuroscience and receptor-targeted therapeutics.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Chemical Research: Used as a specialized building block in medicinal chemistry for structure-activity relationship (SAR) studies and novel compound library development.
• API Development: Serves as a key scaffold in the research and process development of new Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Employed in chiral synthesis due to its defined (R)-configuration, enabling the production of enantiomerically pure compounds.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(R)-3-((1-Methylpyrrolidin-2-Yl)Methyl)-1H-Indol-4-Ol
CAS No.	250672-65-2
Molecular Formula	C15H20N2O
Molecular Weight	244.34 g/mol
Synonyms	(R)-3-((1-Methyl-2-pyrrolidinyl)methyl)-1H-indol-4-ol; (R)-4-Hydroxy-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole; (R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-1H-indol-4-ol; (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-1H-indol-4-ol; 4-Hydroxy-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indole, (R)-; (R)-3-(1-Methylpyrrolidin-2-ylmethyl)-1H-indol-4-ol; (R)-3-((1-Methyl-2-pyrrolidinyl)methyl)-4-indolol
EINECS	Contact for details

Quality Control

Our (R)-3-((1-Methylpyrrolidin-2-Yl)Methyl)-1H-Indol-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥98.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.