Description

(Z)-2-(5-Chloro-2-(Tritylamino)Thiazol-4-Yl)-2-Methoxyiminoacetic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key synthetic precursor in the development of active pharmaceutical ingredients (APIs), particularly within the cephalosporin class of antibiotics. It is primarily required by pharmaceutical manufacturers, R&D laboratories, and fine chemical synthesis specialists focused on producing next-generation antimicrobial agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced cephalosporin antibiotics.
• API Synthesis: Used in the production chain of active pharmaceutical ingredients (APIs) for broad-spectrum antibacterial medications.
• Research & Development: Serves as a key reagent in medicinal chemistry for developing novel antimicrobial compounds and studying structure-activity relationships.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for high-value, complex organic molecules.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for antibiotic production.

Basic Information

Product Name	(Z)-2-(5-Chloro-2-(Tritylamino)Thiazol-4-Yl)-2-Methoxyiminoacetic Acid
CAS No.	250597-83-2
Molecular Formula	C25H20ClN3O3S
Molecular Weight	477.96 g/mol
Synonyms	(Z)-2-(5-Chloro-2-(Tritylamino)-1,3-thiazol-4-yl)-2-(methoxyimino)acetic Acid; 7-ACA Side Chain Derivative; Cephalosporin Intermediate; (Z)-2-(5-Chloro-2-((Triphenylmethyl)amino)-4-thiazolyl)-2-(methoxyimino)acetic Acid; 2-(5-Chloro-2-(tritylamino)thiazol-4-yl)-2-methoxyiminoacetic Acid (Z-isomer); 250597-83-2; Trityl-protected Amino Thiazole Acetic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of (Z)-2-(5-Chloro-2-(Tritylamino)Thiazol-4-Yl)-2-Methoxyiminoacetic Acid adheres to stringent quality management systems, ensuring batch-to-batch consistency for critical pharmaceutical applications. The material is manufactured under controlled conditions and undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, related substances, and residual solvents is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.