Description

Carbamic Acid, 3-Azabicyclo[4.1.0]Hept-7-Yl-, 1,1-Dimethylethyl Ester is a specialized bicyclic carbamate derivative, serving as a critical protected intermediate in advanced organic synthesis. Its value lies in providing a sterically hindered, base-labile protecting group for amines, enabling complex multi-step reactions in sensitive molecule construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly those requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those containing fused azabicyclic ring systems.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where specific stereochemistry and amine protection are required.
• Peptide Mimetics & PROTACs: Facilitates the introduction of constrained, three-dimensional structures into peptide backbones and linker chemistries for targeted protein degradation.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in enantioselective catalytic reactions.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry, particularly in studies involving strained ring systems and protective group strategies.
• Fine Chemical Production: Employed in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	Carbamic Acid, 3-Azabicyclo[4.1.0]Hept-7-Yl-, 1,1-Dimethylethyl Ester
CAS No.	250275-27-5
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	tert-Butyl 3-azabicyclo[4.1.0]heptane-3-carboxylate; 3-Azabicyclo[4.1.0]heptane-3-carboxylic acid, 1,1-dimethylethyl ester; 3-Boc-3-azabicyclo[4.1.0]heptane; 3-N-Boc-3-azabicyclo[4.1.0]heptane; 3-(tert-Butoxycarbonyl)-3-azabicyclo[4.1.0]heptane; Bicyclo[4.1.0]heptane, 3-[(1,1-dimethylethoxy)carbonyl]-; 3-Azabicyclo[4.1.0]heptane-3-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, 3-Azabicyclo[4.1.0]Hept-7-Yl-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.