Description

(R)-6-Methylamino-6,7,8,9-Tetrahydro-5H-Carbazole-3-Carbonitrile is a chiral, nitrogen-containing heterocyclic compound that serves as a sophisticated building block in advanced organic synthesis. Its value lies in its unique carbazole core and functional groups, which make it a critical intermediate for constructing complex molecules with specific stereochemistry. This high-purity intermediate is primarily needed by pharmaceutical research and development organizations for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemical companies developing next-generation crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific biological activity is required.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a chiral scaffold in the development of new catalytic systems for stereoselective transformations.
• Material Science Precursor: Potential building block for organic electronic materials, given the electron-rich nature of the carbazole moiety.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	(R)-6-Methylamino-6,7,8,9-Tetrahydro-5H-Carbazole-3-Carbonitrile
CAS No.	247939-84-0
Molecular Formula	C14H15N3
Molecular Weight	225.29 g/mol
Synonyms	(R)-6-(Methylamino)-5,6,7,8,9,9a-hexahydrocarbazole-3-carbonitrile; (6R)-6-(Methylamino)-6,7,8,9-tetrahydro-5H-carbazole-3-carbonitrile; 3-Cyano-(6R)-6-methylamino-6,7,8,9-tetrahydro-5H-carbazole; (R)-enantiomer of 6-Methylamino-6,7,8,9-tetrahydro-5H-carbazole-3-carbonitrile; (R)-Methylamino-tetrahydrocarbazole-carbonitrile
EINECS	Contact for details

Quality Control

Our (R)-6-Methylamino-6,7,8,9-Tetrahydro-5H-Carbazole-3-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.