Description

4-(2-Aminoethyl)Amino-3-Hydroxytetrahydrothiophene, 1,1-Dioxide is a high-purity, functionalized sulfolane derivative of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block and intermediate, prized for its unique combination of a sulfone group, hydroxyl functionality, and a diamine moiety. Pharmaceutical and agrochemical R&D teams need it for developing novel active ingredients, particularly where stereochemistry and specific molecular interactions are critical.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel drug candidates, particularly in protease inhibitor and enzyme-targeted therapies.
• Agrochemical Synthesis: Building block for creating advanced, high-selectivity herbicides and fungicides with complex molecular architectures.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal complexation.
• Advanced Material Research: Intermediate for synthesizing functional polymers and specialty chemicals with sulfone and amine groups.
• Bioconjugation Chemistry: Potential use in linker molecules for antibody-drug conjugates (ADCs) due to its reactive amine and hydroxyl groups.
• Chemical Biology Probes: Serves as a core structure for designing molecular probes to study biological pathways.

Basic Information

Item	Detail
Product Name	4-(2-Aminoethyl)Amino-3-Hydroxytetrahydrothiophene, 1,1-Dioxide
CAS No.	247109-21-3
Molecular Formula	C6H14N2O3S
Molecular Weight	194.25 g/mol
Synonyms	4-[(2-Aminoethyl)amino]-3-hydroxytetrahydrothiophene 1,1-dioxide; 3-Hydroxy-4-[(2-aminoethyl)amino]thiolane 1,1-dioxide; 4-(2-Aminoethylamino)-3-hydroxytetrahydrothiophene-1,1-dioxide; Aminoethylaminohydroxytetrahydrothiophene dioxide; Functionalized sulfolane derivative; Chiral sulfolane amine
EINECS	Contact for details

Quality Control

Our 4-(2-Aminoethyl)Amino-3-Hydroxytetrahydrothiophene, 1,1-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.