Description

Bicyclo[2.2.1]Hept-2-Ene-2,3-Dicarboxylic Acid, 5-Amino-, (1R,4R,5S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic amino acid derivative with significant utility in advanced organic synthesis. This compound serves as a sophisticated chiral building block and ligand precursor, enabling the construction of complex molecular architectures with precise stereocontrol. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric catalysis and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Chiral Ligand Synthesis: A key precursor for developing novel, enantioselective catalysts used in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• Pharmaceutical Intermediates: Serves as a critical building block in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and metabolic diseases.
• Advanced Material Research: Used in the development of specialty polymers and functional materials where its rigid bicyclic structure imparts specific mechanical or optical properties.
• Agrochemical Synthesis: Employed in the research and development of new-generation, stereospecific pesticides and herbicides.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, exploring new synthetic pathways and reaction mechanisms.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability and conformational rigidity for biological evaluation.

Basic Information

Item	Detail
Product Name	Bicyclo[2.2.1]Hept-2-Ene-2,3-Dicarboxylic Acid, 5-Amino-, (1R,4R,5S)-Rel- (9Ci)
CAS No.	247028-54-2
Molecular Formula	C9H11NO4
Molecular Weight	197.19 g/mol
Synonyms	5-Aminobicyclo[2.2.1]hept-2-ene-2,3-dicarboxylic acid, (1R,4R,5S)-rel-; rel-(1R,4R,5S)-5-Aminobicyclo[2.2.1]hept-2-ene-2,3-dicarboxylic acid; Bicyclo[2.2.1]hept-2-ene-2,3-dicarboxylic acid, 5-amino-, (1R,4R,5S)-rel-; 5-Amino-2-norbornene-2,3-dicarboxylic acid (stereoisomer); Amino-NBD acid derivative; Chiral NBDA precursor; CAS 247028-54-2
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[2.2.1]Hept-2-Ene-2,3-Dicarboxylic Acid, 5-Amino-, (1R,4R,5S)-Rel- (9Ci) is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.