Description

Benzene, 1-(Cyclopropylidenemethyl)-4-Fluoro- (9Ci) is a specialized fluorinated aromatic compound featuring a cyclopropylidene substituent. This unique molecular architecture makes it a valuable advanced intermediate for the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where its distinct structure enables the exploration of new chemical space and property profiles.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and insecticides that require fluorinated aromatic cores for enhanced activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand Synthesis: Employed in organometallic chemistry for creating novel ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to synthesize fluorescent or bioactive probes for studying biological pathways and protein interactions.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic synthesis, including cross-coupling and cycloaddition reactions.

Basic Information

Product Name	Benzene, 1-(Cyclopropylidenemethyl)-4-Fluoro- (9Ci)
CAS No.	246180-26-7
Molecular Formula	C11H9F
Molecular Weight	160.19 g/mol
Synonyms	4-Fluoro-1-(cyclopropylidenemethyl)benzene; 1-(Cyclopropylidenemethyl)-4-fluorobenzene; 4-Fluorobenzylidenecyclopropane; (4-Fluorophenyl)(cyclopropylidene)methane; Benzene, 1-(cyclopropylidenemethyl)-4-fluoro-; 246180-26-7; p-Fluoro-(cyclopropylidenemethyl)benzene
EINECS	Contact for details

Quality Control

Our production of Benzene, 1-(Cyclopropylidenemethyl)-4-Fluoro- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and MS, to verify identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.