Description

1H-Indole,3-(2-Chloroethyl)-5-Fluoro- CAS NO 245762-55-4 is a high-value, halogenated indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both chloroethyl and fluoro substituents on the indole core, makes it a versatile building block for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development teams engaged in the synthesis of novel therapeutic agents and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides due to its bioactive indole structure.
• Chemical Research: Serves as a specialized building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential intermediate in the development of organic electronic materials and functional dyes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	1H-Indole,3-(2-Chloroethyl)-5-Fluoro-
CAS No.	245762-55-4
Molecular Formula	C10H9ClFN
Molecular Weight	197.64 g/mol
Synonyms	5-Fluoro-3-(2-chloroethyl)indole; 3-(2-Chloroethyl)-5-fluoro-1H-indole; 5-Fluoro-3-(2-chloroethyl)-1H-indole; 1H-Indole-3-ethanol, 5-fluoro-, 2-chloro derivative; 5-Fluoro-3-(β-chloroethyl)indole; 3-(β-Chloroethyl)-5-fluoroindole; 5-Fluoro-3-(2-chloroethyl)indole
EINECS	Contact for details

Quality Control

Our 1H-Indole,3-(2-Chloroethyl)-5-Fluoro- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against established specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.