Description

1-Azabicyclo[2.2.1]Heptane-3-Thiol,(1R,3S,4S)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic thiol building block. This compound is valued for its unique constrained scaffold and functional handle, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides with specific stereochemical requirements for enhanced activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Material Science Research: Acts as a functional monomer or cross-linker in the development of specialty polymers with specific mechanical or chemical properties.

Basic Information

Product Name	1-Azabicyclo[2.2.1]Heptane-3-Thiol,(1R,3S,4S)-Rel-(9Ci)
CAS No.	245676-20-4
Molecular Formula	C6H11NS
Molecular Weight	129.22 g/mol
Synonyms	(1R,3S,4S)-1-Azabicyclo[2.2.1]heptane-3-thiol; rel-(1R,3S,4S)-1-Azabicyclo[2.2.1]heptane-3-thiol; (1R,3S,4S)-3-Mercapto-1-azabicyclo[2.2.1]heptane; 3-Thio-1-azabicyclo[2.2.1]heptane, (1R,3S,4S)-rel-; Bicyclic thiol amine; Endo-3-mercapto-1-azabicyclo[2.2.1]heptane (relative configuration)
EINECS	Contact for details

Quality Control

Our production of 1-Azabicyclo[2.2.1]Heptane-3-Thiol,(1R,3S,4S)-Rel-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be kept sealed and only opened under an inert environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (for specified isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.