Description

2-Oxazolemethanol,4,5-Dihydro-Alpha,α-Dimethyl-4-(1-Methylethyl)-,(4R)-(9Ci) is a chiral, substituted oxazoline derivative of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block and ligand precursor, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research and development chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for asymmetric synthesis and catalysis.

Application

• Chiral Auxiliary and Ligand Synthesis: Serves as a key precursor for the development of novel chiral ligands used in asymmetric catalysis, such as hydrogenation and C-C bond formation.
• Pharmaceutical Intermediate: Employed in the research and scalable synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Agrochemical Development: Used in the creation of enantiomerically defined active ingredients for herbicides, fungicides, and insecticides.
• Fine Chemical Synthesis: Acts as a specialized building block for complex natural products, flavors, and fragrances.
• Academic and Industrial Research: A valuable tool for methodological development in organic chemistry and catalysis research.
• Material Science Precursor: Potential use in the synthesis of chiral polymers or functionalized surfaces with specific stereochemical properties.

Basic Information

Product Name	2-Oxazolemethanol,4,5-Dihydro-Alpha,α-Dimethyl-4-(1-Methylethyl)-,(4R)-(9Ci)
CAS No.	245503-15-5
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(4R)-4,5-Dihydro-α,α-dimethyl-4-(1-methylethyl)-2-oxazolemethanol; (R)-4-Isopropyl-2,2-dimethyl-4,5-dihydrooxazole-4-methanol; (R)-4-(2-Hydroxy-1,1-dimethylethyl)-2,2-dimethyl-4,5-dihydrooxazole; 2-Oxazolylmethanol, 4,5-dihydro-α,α-dimethyl-4-(1-methylethyl)-, (4R)-; (R)-Valinol-derived oxazoline methanol; Chiral oxazoline alcohol; (R)-4-Isopropyl-4,5-dihydro-2,2-dimethyl-4-oxazolemethanol
EINECS	Contact for details

Quality Control

Our 2-Oxazolemethanol,4,5-Dihydro-Alpha,α-Dimethyl-4-(1-Methylethyl)-,(4R)-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity determination by HPLC, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment to guarantee traceability and support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.