Description

L-Alanine, n-(Chlorophenoxyphosphinyl)-, Ethyl Ester is a specialized organophosphorus compound that serves as a key synthetic intermediate. Its molecular structure, featuring a phosphinyl group linked to a chlorophenoxy moiety and an alanine-derived ester, makes it valuable for constructing complex bioactive molecules. This compound is primarily sought by research and development teams in the agrochemical and pharmaceutical industries for the synthesis of novel active ingredients.

Application

• Agrochemical Intermediate: A critical building block in the synthesis of advanced insecticides, herbicides, and plant growth regulators.
• Pharmaceutical Research: Used in medicinal chemistry for the development of prodrugs and enzyme inhibitors, particularly targeting serine hydrolases.
• Chemical Biology Probe Synthesis: Employed in the creation of activity-based probes (ABPs) for studying protein function and interactions.
• Peptidomimetic Development: Serves as a phosphorylated amino acid analog for constructing modified peptides with enhanced stability or biological activity.
• Ligand and Catalyst Precursor: Utilized in organometallic chemistry and catalysis research as a precursor for chiral ligands.

Basic Information

Product Name	L-Alanine, n-(Chlorophenoxyphosphinyl)-, Ethyl Ester
CAS No.	245078-14-2
Molecular Formula	C11H15ClNO5P
Molecular Weight	307.67 g/mol
Synonyms	Ethyl (2S)-2-[[(4-Chlorophenoxy)phosphinyl]amino]propanoate; L-Alanine, N-[(4-chlorophenoxy)phosphinyl]-, ethyl ester; N-(4-Chlorophenoxyphosphinyl)-L-alanine ethyl ester; (S)-Ethyl 2-((4-chlorophenoxy)(hydroxy)phosphorylamino)propanoate; Alanine, N-(chlorophenoxyphosphinyl)-, ethyl ester, L-; Phosphoramidic acid, N-(1-ethoxy-1-oxopropan-2-yl)-, O-(4-chlorophenyl) ester
EINECS	Contact for details

Quality Control

Every batch of L-Alanine, n-(Chlorophenoxyphosphinyl)-, Ethyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development applications. A detailed Certificate of Analysis (COA) including results for assay, chiral purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee (L-Isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.