Description

1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid Methyl Ester is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting protein kinases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of fused heterocyclic systems due to its reactive pyrrolopyridine core and sulfonyl protecting group.
• Biochemical Tool Compound: Serves as a starting material for creating probes and inhibitors used in biochemical and cellular assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid Methyl Ester
CAS No.	245064-81-7
Molecular Formula	C₁₇H₁₄N₂O₄S
Molecular Weight	342.37 g/mol
Synonyms	Methyl 1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 1-(phenylsulfonyl)-, methyl ester; 1-Benzenesulfonyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; 1-Phenylsulfonyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; CAS 245064-81-7
EINECS	Contact for details

Quality Control

Our production of 1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.