Description

Bicyclo[3.1.0]Hexan-2-One, 1-Hydroxy-5-(1-Methylethyl)- (9Ci) is a high-purity, specialized bicyclic ketone derivative with a unique bridged-ring structure. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate for the synthesis of complex bioactive molecules. It is primarily needed by research institutions, fine chemical manufacturers, and pharmaceutical R&D departments engaged in developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex polycyclic or bridged-ring architectures.
• Asymmetric Synthesis: Chiral synthon for constructing stereocenters in medicinal chemistry and total synthesis projects, leveraging its inherent hydroxyl and ketone functionalities.
• Agrochemical Research: Building block for developing novel pesticides and herbicides where the bicyclo[3.1.0]hexane scaffold may confer unique biological activity.
• Flavor & Fragrance Chemistry: Potential intermediate for creating complex, musky, or woody odorants due to its rigid, camphor-like structural framework.
• Material Science Research: Monomer or cross-linking agent candidate for developing specialty polymers with specific thermal or mechanical properties.
• Academic & Process Chemistry: Valuable reagent for methodological studies in organic synthesis, including ring-opening, functionalization, and cycloaddition reactions.

Basic Information

Product Name	Bicyclo[3.1.0]Hexan-2-One, 1-Hydroxy-5-(1-Methylethyl)- (9Ci)
CAS No.	244793-46-2
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	1-Hydroxy-5-isopropylbicyclo[3.1.0]hexan-2-one; 5-Isopropyl-1-hydroxybicyclo[3.1.0]hexan-2-one; 1-Hydroxy-5-(propan-2-yl)bicyclo[3.1.0]hexan-2-one; Bicyclo[3.1.0]hexan-2-one, 1-hydroxy-5-(1-methylethyl)-; 244793-46-2; Hydroxyisopropylbicyclohexanone
EINECS	Contact for details

Quality Control

Our production of Bicyclo[3.1.0]Hexan-2-One, 1-Hydroxy-5-(1-Methylethyl)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, GC, NMR, and chiral analysis, to meet precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources, strong oxidizing agents, and incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.