Description

4-Chloro-2-Iodobenzyl Alcohol is a versatile halogenated benzyl alcohol derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both chloro and iodo substituents, makes it a valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators that require halogenated aromatic cores.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and cross-coupling reactions, such as Suzuki and Sonogashira couplings.
• Material Science Research: Intermediate for synthesizing organic electronic materials, liquid crystals, and advanced polymers where halogen atoms modulate material properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.
• Academic and R&D Laboratories: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-Chloro-2-Iodobenzyl Alcohol
CAS No.	244104-55-0
Molecular Formula	C7H6ClIO
Molecular Weight	284.48 g/mol
Synonyms	(4-Chloro-2-iodophenyl)methanol; 2-Iodo-4-chlorobenzyl alcohol; 1-Chloro-4-(hydroxymethyl)-3-iodobenzene; 4-Chloro-2-iodo-benzenemethanol; Benzenemethanol, 4-chloro-2-iodo-; α-Hydroxy-4-chloro-2-iodotoluene; 4-Chloro-2-iodobenzylalcohol
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Iodobenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production facilities and processes are designed to meet the stringent requirements of cGMP for advanced intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature (store away from light), the container should be opaque or stored in dark conditions. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.