Description

Bicyclo[2.2.1]Heptane-2,6-Dicarboxylic Acid, 2-Amino-, (1R,2R,4S,6R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid bicyclic framework and multiple functional groups make it a valuable precursor for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric catalysis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring rigid, three-dimensional scaffolds.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of sophisticated chiral ligands for transition metal catalysis, enabling highly enantioselective transformations.
• Agrochemical Research: Employed in the design and synthesis of new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Monomer: Acts as a functional monomer for creating specialty polymers with unique thermal and mechanical properties derived from its strained bicyclic structure.
• Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and for studying structure-activity relationships (SAR) in chemical biology.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2,6-Dicarboxylic Acid, 2-Amino-, (1R,2R,4S,6R)-Rel- (9Ci)
CAS No.	243986-89-2
Molecular Formula	C10H15NO4
Molecular Weight	213.23 g/mol
Synonyms	(1R,2R,4S,6R)-2-Aminobicyclo[2.2.1]heptane-2,6-dicarboxylic acid; rel-(1R,2R,4S,6R)-2-Aminobicyclo[2.2.1]heptane-2,6-dicarboxylic acid; 2-Aminonorbornane-2,6-dicarboxylic acid (stereospecific); 2-Amino-2,6-norbornanedicarboxylic acid; Bicyclo[2.2.1]heptane-2,6-dicarboxylic acid, 2-amino-, (1R,2R,4S,6R)-rel-; 243986-89-2; Chiral Norbornane Amino Diacid
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-2,6-Dicarboxylic Acid, 2-Amino-, (1R,2R,4S,6R)-Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and scale-up. Each lot undergoes comprehensive analytical characterization, including chiral purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (specified isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.