Description

tert-Butyl 3-(1H-Indol-1-Yl)Propylcarbamate is a specialized, high-purity organic building block of significant interest in advanced chemical synthesis. This compound serves as a crucial protected intermediate, enabling the controlled introduction of the indole pharmacophore into complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. Its defined structure and purity are essential for ensuring reproducibility and efficacy in downstream synthetic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways where the indole scaffold is prevalent.
• Peptide Mimetics & Conjugation: Used to incorporate indole-based side chains into peptide backbones or for bioconjugation strategies in medicinal chemistry.
• Organic Synthesis Research: Serves as a versatile reagent for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Agrochemical Development: Employed in the research phase for creating new crop protection agents and plant growth regulators.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or specialty polymers requiring specific indole functionalities.

Basic Information

Product Name	tert-Butyl 3-(1H-Indol-1-Yl)Propylcarbamate
CAS No.	243841-08-9
Molecular Formula	C₁₆H₂₂N₂O₂
Molecular Weight	274.36 g/mol
Synonyms	1H-Indole-1-propanamine, N-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl N-[3-(1H-indol-1-yl)propyl]carbamate; 1-(3-((tert-Butoxycarbonyl)amino)propyl)-1H-indole; Boc-3-(1H-indol-1-yl)propylamine; N-Boc-3-(indol-1-yl)propylamine; tert-Butyl (3-(1H-indol-1-yl)propyl)carbamate; 243841-08-9; Carbamic acid, N-[3-(1H-indol-1-yl)propyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(1H-Indol-1-Yl)Propylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.