Description

5-[(2R)-2-Aminopropyl]-1-[3-(Benzoyloxy)Propyl]-2,3-Dihydro-7-Carbonitrile-1H-Indole is a high-purity, chiral indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active molecules. It is primarily sought by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of central nervous system (CNS) active compounds and other therapeutic agents.
• Medicinal Chemistry Research: A versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in route scouting and scale-up studies for the production of complex active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Employed as a chiral building block to introduce stereochemical complexity into target molecules.
• Biochemical Research: Potential ligand or probe in the study of biological receptors and enzyme systems.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	5-[(2R)-2-Aminopropyl]-1-[3-(Benzoyloxy)Propyl]-2,3-Dihydro-7-Carbonitrile-1H-Indole
CAS No.	239463-72-0
Molecular Formula	C22H23N3O2
Molecular Weight	361.44 g/mol
Synonyms	(R)-5-(2-Aminopropyl)-1-(3-(benzoyloxy)propyl)-2,3-dihydro-1H-indole-7-carbonitrile; 1H-Indole-7-carbonitrile, 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-; 239463-72-0; 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile; Chiral Indole Carbonitrile Derivative; Benzoyloxypropyl Aminopropyl Dihydroindolecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-[(2R)-2-Aminopropyl]-1-[3-(Benzoyloxy)Propyl]-2,3-Dihydro-7-Carbonitrile-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for chiral purity and assay, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.