Description

Isopropyltriphenylphosphonium Bromide And Sodium Amide CAS NO 238083-06-2 is a highly reactive organometallic reagent complex, combining a Wittig reagent precursor with a strong base. This combination is critical for facilitating challenging deprotonation and carbon-carbon bond formation reactions in synthetic organic chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the production of active pharmaceutical ingredients (APIs), especially in sterically hindered olefination reactions.
• Agrochemical Manufacturing: Used in the synthesis of complex pesticide and herbicide molecules requiring specific alkene geometries.
• Advanced Material Research: Facilitates the creation of novel polymers and liquid crystals with tailored properties via precise olefination.
• Academic & Industrial R&D: Employed in method development and exploratory synthesis for new chemical entities.
• Fine Chemical Production: Enables the synthesis of specialty chemicals, flavors, and fragrances requiring high-purity alkenes.
• Catalyst Ligand Preparation: Serves as a precursor for generating specialized phosphine ligands used in catalysis.

Basic Information

Product Name	Isopropyltriphenylphosphonium Bromide And Sodium Amide
CAS No.	238083-06-2
Molecular Formula	C21H22BrP • NaNH2
Molecular Weight	Contact for details
Synonyms	Isopropyltriphenylphosphonium Bromide Sodium Amide Complex; Sodium Amide Isopropyltriphenylphosphonium Bromide Adduct; (Isopropyl)triphenylphosphonium Bromide - Sodium Amide; Wittig Reagent Base Complex; PPNBr-NaNH2; ITPPB-NaNH2; Sodium amide compd. with (1-methylethyl)triphenylphosphonium bromide (1:1); 1-Methylethyltriphenylphosphonium bromide, compound with sodium amide (1:1)
EINECS	Contact for details

Quality Control

Our Isopropyltriphenylphosphonium Bromide And Sodium Amide is manufactured under strict quality protocols. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and titration, to ensure high chemical purity and consistent reactivity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, oxidizers, and water.

Specification

Item	Specification
Appearance	Off-white to beige powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Active Base Content (Titration)	Contact for details
Water Content (KF)	≤ 1.0%
Solubility	Soluble in THF, DMF; reacts with water, alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.