Description

9-Bromo-7,12-Dihydrobenzo[2,3]Azepino[4,5-B]Indole-6(5H)-Thione is a sophisticated heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in medicinal chemistry. Its unique fused-ring structure, incorporating bromine and a thione group, makes it invaluable for the synthesis of novel bioactive molecules targeting complex diseases. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical R&D and fine chemical synthesis who require reliable, high-quality building blocks for drug discovery programs.

Application

This specialized brominated heterocycle is designed for advanced synthetic applications. Key uses include:

• Pharmaceutical Intermediate: Serves as a core scaffold for the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Medicinal Chemistry Research: Used as a key building block for structure-activity relationship (SAR) studies and library synthesis due to its reactive bromine and thione functional groups.
• Organic Synthesis Reagent: Acts as a precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) or nucleophilic substitution.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Material Science Research: Investigated as a potential monomer or dopant for creating organic electronic materials with specific optoelectronic properties.

Basic Information

Item	Details
Product Name	9-Bromo-7,12-Dihydrobenzo[2,3]Azepino[4,5-B]Indole-6(5H)-Thione
CAS No.	237430-35-2
Molecular Formula	C16H11BrN2S
Molecular Weight	343.24 g/mol
Synonyms	9-Bromo-5,7,12,12b-tetrahydro-6H-azepino[4,5-b]indole-6-thione; 9-Bromobenzo[2,3]azepino[4,5-b]indole-6(5H)-thione; 237430-35-2; 9-Bromo-7,12-dihydro-5H-benzo[2,3]azepino[4,5-b]indole-6-thione; 9-Br-DHBAIT; Azepinoindolethione bromo derivative
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure the integrity of our advanced intermediates. Each batch of 9-Bromo-7,12-Dihydrobenzo[2,3]Azepino[4,5-B]Indole-6(5H)-Thione is subjected to comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and impurity profiles to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container in a well-ventilated area and away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.