Description

1H-Benzimidazole-5-Carboxaldehyde,2-(Hydroxymethyl)-(9Ci) is a functionalized benzimidazole derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both aldehyde and hydroxymethyl substituents, makes it a critical precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and anti-cancer compounds.
• Agrochemical Synthesis: Used in the creation of new fungicides, herbicides, and plant growth regulators that leverage the benzimidazole core for biological activity.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis due to its chelating potential.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers, dyes, and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags or affinity probes for studying biological processes and protein interactions.

Basic Information

Product Name	1H-Benzimidazole-5-Carboxaldehyde,2-(Hydroxymethyl)-(9Ci)
CAS No.	237429-62-8
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	2-(Hydroxymethyl)-1H-benzimidazole-5-carboxaldehyde; 2-Hydroxymethyl-1H-benzimidazole-5-carbaldehyde; 1H-Benzimidazole-5-carboxaldehyde, 2-(hydroxymethyl)-; (2-Hydroxymethyl-1H-benzoimidazol-5-yl)-methanol (tautomeric form); 5-Formyl-2-(hydroxymethyl)benzimidazole; 2-(Hydroxymethyl)-5-formylbenzimidazole; Benzimidazole-5-carboxaldehyde, 2-(hydroxymethyl)- derivative
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-5-Carboxaldehyde,2-(Hydroxymethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.