Description

1H-Benzimidazole-5-Carbonitrile,2-(Hydroxymethyl)-(9Ci) is a high-purity, functionalized benzimidazole derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate complex molecular architectures into their products.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Research: Used in developing new-generation fungicides and herbicides, leveraging the bioactivity of the benzimidazole core.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: Investigated as a building block for electron-transport materials and organic semiconductors due to its conjugated structure.
• Biochemical Probe Development: Utilized in medicinal chemistry to create fluorescent probes or molecular tags for biological imaging and assay development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1H-Benzimidazole-5-Carbonitrile,2-(Hydroxymethyl)-(9Ci)
CAS No.	237429-61-7
Molecular Formula	C9H7N3O
Molecular Weight	173.17 g/mol
Synonyms	2-(Hydroxymethyl)-1H-benzimidazole-5-carbonitrile; 2-Hydroxymethyl-5-cyanobenzimidazole; 1H-Benzimidazole-5-carbonitrile, 2-(hydroxymethyl)-; (2-Hydroxymethyl-1H-benzoimidazol-5-yl)-acetonitrile; 237429-61-7; Benzimidazole-5-carbonitrile, 2-(hydroxymethyl)-; 2-(Hydroxymethyl)-5-cyano-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-5-Carbonitrile,2-(Hydroxymethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.