Description

3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-,(3S)-(9Ci) is a high-purity, chiral isoquinoline derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated building block for the development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of complex heterocyclic compounds targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for constructing complex molecular libraries in drug discovery programs.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric reactions to introduce the (3S)-tetrahydroisoquinoline moiety into target molecules.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and enzyme inhibition studies.
• Fine Chemical Synthesis: Serves as a specialized intermediate for the production of high-value agrochemicals, dyes, or advanced materials.

Basic Information

Product Name	3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-,(3S)-(9Ci)
CAS No.	236429-63-3
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	(3S)-7-Amino-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 7-Amino-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, (3S)-; (S)-7-Amino-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 236429-63-3; (3S)-7-Amino-3,4-dihydro-1H-isoquinoline-3-carboxylic acid; 7-Amino-Tic-OH (S-enantiomer); (S)-7-Amino-Tic; (S)-ATIQ
EINECS	Contact for details

Quality Control

Our 3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-,(3S)-(9Ci) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.