Description

Bicyclo[3.1.0]Hexane-2,6-Dicarboxylic Acid, 2-Amino-3-Fluoro-, (1S,2S,3S,5R,6S)- (9Ci) is a high-purity, stereochemically defined bicyclic amino acid derivative, serving as a sophisticated chiral building block in advanced organic synthesis. Its unique constrained structure and specific stereochemistry make it a valuable scaffold for constructing complex molecules with precise three-dimensional architecture. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring rigid, three-dimensional molecular frameworks.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides where its specific stereochemistry can influence biological activity and selectivity.
• Peptidomimetics & Constrained Peptide Design: Incorporated into peptide chains to induce specific conformational constraints, enhancing metabolic stability and receptor binding affinity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis or as a component in metal-organic frameworks (MOFs).
• Academic & Industrial R&D: Employed in chemical biology and medicinal chemistry research to explore structure-activity relationships (SAR) and novel chemical space.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or advanced materials with unique properties derived from its bicyclic core.

Basic Information

Item	Details
Product Name	Bicyclo[3.1.0]Hexane-2,6-Dicarboxylic Acid, 2-Amino-3-Fluoro-, (1S,2S,3S,5R,6S)- (9Ci)
CAS No.	234085-20-2
Molecular Formula	C9H10FNO4
Molecular Weight	215.18 g/mol
Synonyms	(1S,2S,3S,5R,6S)-2-Amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid; 2-Amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, (1S,2S,3S,5R,6S)-; Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-3-fluoro-, (1S,2S,3S,5R,6S)-; 234085-20-2; (1S,2S,3S,5R,6S)-2-Amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral HPLC, 1H/13C NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.