Description

1-(7-Nitro-1,2,3,4-tetrahydroisoquinolin-3-yl)ethenol is a specialized nitro-substituted tetrahydroisoquinoline derivative, serving as a critical advanced pharmaceutical intermediate for modern drug discovery and development. This compound matters because it provides a versatile and functionalized scaffold essential for synthesizing complex molecules with potential biological activity. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating novel therapeutic agents, particularly within neurological and cardiovascular research domains.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of new active pharmaceutical ingredients (APIs).
• Neurological Research Compounds: Used in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Precursor for Alkaloid Analogues: Acts as a starting material for creating novel tetrahydroisoquinoline-based alkaloid analogues with modified biological properties.
• Medicinal Chemistry & Lead Optimization: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead molecules.
• Contract Research & Development (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and pharmacological studies.

Basic Information

Product Name	1-(7-Nitro-1,2,3,4-tetrahydroisoquinolin-3-yl)ethenol
CAS No.	233272-36-1
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	1-(7-Nitro-3,4-dihydro-1H-isoquinolin-3-yl)ethanol; 1-(7-Nitro-1,2,3,4-tetrahydro-3-isoquinolinyl)ethanol; 3-(1-Hydroxyethyl)-7-nitro-1,2,3,4-tetrahydroisoquinoline; 7-Nitro-3-(1-hydroxyethyl)-1,2,3,4-tetrahydroisoquinoline; 1-(7-Nitro-1,2,3,4-tetrahydroisoquinolin-3-yl)ethanol; 233272-36-1
EINECS	Contact for details

Quality Control

Our 1-(7-Nitro-1,2,3,4-tetrahydroisoquinolin-3-yl)ethenol is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.