Description

5-Nitro-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid is a specialized heterocyclic carboxylic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique nitro-substituted tetrahydroisoquinoline scaffold, which is a privileged structure for developing bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, particularly in the areas of central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize novel pharmacophores.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex heterocyclic compounds and fine chemicals.
• Academic & R&D Laboratories: Employed in methodological development and as a reference standard in analytical studies.

Basic Information

Product Name	5-Nitro-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid
CAS No.	233272-35-0
Molecular Formula	C10H10N2O4
Molecular Weight	222.20 g/mol
Synonyms	3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-5-nitro-; 5-Nitro-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 5-Nitro-THIQ-3-COOH; 233272-35-0; 5-Nitro-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 5-Nitro-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Nitro-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards expected in fine chemical and pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.