Description

5-Bromo-4-Chloro-4,5,5-Trifluoropent-2-En-1-Ol is a high-value, multi-halogenated fluorinated building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring bromine, chlorine, and fluorine substituents on an unsaturated alcohol backbone, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its specific reactivity profile allows for selective transformations, enabling the efficient creation of diverse chemical libraries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity and environmental stability.
• Fluorinated Material Precursor: Serves as a building block for specialty polymers, liquid crystals, or organic electronic materials that require specific fluorinated segments.
• Cross-Coupling Reactions: The bromine and chlorine atoms provide orthogonal handles for versatile metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi, Stille) to form complex carbon-carbon bonds.
• Nucleophilic Substitution Substrate: The halogenated carbons are reactive sites for nucleophilic substitution, allowing for the introduction of various heteroatoms and functional groups.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes, leveraging the distinct properties of its halogen atoms.

Basic Information

Product Name	5-Bromo-4-Chloro-4,5,5-Trifluoropent-2-En-1-Ol
CAS No.	232602-81-2
Molecular Formula	C5H5BrClF3O
Molecular Weight	253.44 g/mol
Synonyms	4,5,5-Trifluoro-5-bromo-4-chloropent-2-en-1-ol; 2-Penten-1-ol, 5-bromo-4-chloro-4,5,5-trifluoro-; 5-Bromo-4-chloro-4,5,5-trifluoro-2-penten-1-ol; 4,5,5-Trifluoro-4-chloro-5-bromopent-2-en-1-ol; Bromochlorotrifluoropentenol
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-4,5,5-Trifluoropent-2-En-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.