Description

1-(4-Boc-Amino-Phenyl)-Ethanol is a high-purity, protected amino alcohol derivative, serving as a critical chiral building block in advanced organic synthesis. Its core value lies in providing a versatile, Boc-protected aromatic amine handle that is essential for constructing complex molecular architectures with precise stereochemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Peptidomimetic Chemistry: Used to incorporate aromatic, alcohol-functionalized amino acid analogs into peptide backbones to enhance stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Agrochemical Synthesis: Employed in the research and production of advanced, stereochemically-defined pesticides and herbicides.
• Material Science Research: Acts as a monomer or functionalization agent in the synthesis of specialized polymers and dendrimers.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring protected aromatic amino alcohol functionality.

Basic Information

Product Name	1-(4-Boc-Amino-Phenyl)-Ethanol
CAS No.	232597-44-3
Molecular Formula	C13H19NO3
Molecular Weight	237.29 g/mol
Synonyms	1-[4-[(tert-Butoxycarbonyl)amino]phenyl]ethanol; 4-(1-Hydroxyethyl)phenylcarbamic Acid tert-Butyl Ester; N-Boc-4-(1-Hydroxyethyl)aniline; tert-Butyl [4-(1-hydroxyethyl)phenyl]carbamate; 1-(4-(Boc-amino)phenyl)ethan-1-ol; N-(tert-Butoxycarbonyl)-4-(1-hydroxyethyl)aniline; 4-(1-Hydroxyethyl)aniline N-Boc derivative
EINECS	Contact for details

Quality Control

Our 1-(4-Boc-Amino-Phenyl)-Ethanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles. We adhere to relevant ICH guidelines and our quality commitment supports compliance in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.