Description

2-Thiophenecarbonitrile, 5-(Hydroxymethyl)-3-Methyl- (9Ci) is a high-value, multi-functional heterocyclic building block featuring both nitrile and hydroxymethyl substituents on a thiophene core. This compound matters for its versatility as a key synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of conductive polymers, organic semiconductors, and advanced polymeric materials.
• Ligand and Catalyst Development: The nitrile and hydroxymethyl groups make it a valuable starting point for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex fine chemicals and specialty dyes.

Basic Information

Product Name	2-Thiophenecarbonitrile, 5-(Hydroxymethyl)-3-Methyl- (9Ci)
CAS No.	232281-11-7
Molecular Formula	C7H7NOS
Molecular Weight	153.20 g/mol
Synonyms	5-(Hydroxymethyl)-3-methylthiophene-2-carbonitrile; 3-Methyl-5-(hydroxymethyl)thiophene-2-carbonitrile; 5-Hydroxymethyl-3-methyl-2-thiophenecarbonitrile; 2-Cyano-5-hydroxymethyl-3-methylthiophene; 232281-11-7; 5-(Hydroxymethyl)-3-methyl-2-thiophenecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarbonitrile, 5-(Hydroxymethyl)-3-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.