Description

5-Aminomethyl-Thiophene-3-Carbonitrile is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its bifunctional structure, featuring both an aminomethyl group and a nitrile moiety on a thiophene core, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold's bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the development of novel conductive polymers, organic semiconductors, and advanced materials.
• Ligand and Catalyst Development: The aminomethyl group can be functionalized to create novel chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Chemistry: Acts as a starting material for synthesizing specialized heterocyclic dyes and functional colorants.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific scaffold.

Basic Information

Product Name	5-Aminomethyl-Thiophene-3-Carbonitrile
CAS No.	232280-88-5
Molecular Formula	C7H8N2S
Molecular Weight	152.22 g/mol
Synonyms	(3-Cyano-5-thienyl)methanamine; 3-Cyano-5-thiophenemethylamine; 5-(Aminomethyl)thiophene-3-carbonitrile; 3-Thiophenecarbonitrile, 5-(aminomethyl)-; 5-Aminomethyl-3-cyanothiophene; 5-(Aminomethyl)-3-thiophenecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Aminomethyl-Thiophene-3-Carbonitrile is produced and tested under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.