Description

4-Aminomethyl-Thiophene-2-Carbonitrile is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its bifunctional structure, featuring both an aminomethyl group and a nitrile on a thiophene core, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) agents and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold's bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the development of conductive polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: The aminomethyl and nitrile functionalities allow for its use in creating novel chelating ligands for metal catalysis.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	4-Aminomethyl-Thiophene-2-Carbonitrile
CAS No.	232280-77-2
Molecular Formula	C6H6N2S
Molecular Weight	138.19 g/mol
Synonyms	2-Cyano-4-thiophenemethylamine; (2-Cyano-4-thienyl)methanamine; 4-(Aminomethyl)thiophene-2-carbonitrile; 2-Thiophenecarbonitrile, 4-(aminomethyl)-; 4-Aminomethyl-2-cyanothiophene; 4-(Aminomethyl)-2-thiophenecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Aminomethyl-Thiophene-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.