Description

2-Bromo-1-Thiazol-5-Yl-Ethanone Hydrobromide is a high-purity organic salt derivative of a thiazole ketone, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, providing both a reactive bromoacetyl group and a thiazole heterocycle, which are essential for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Research: Used to develop new herbicides, fungicides, or insecticides by incorporating the thiazole moiety into active molecules.
• Chemical Biology Probe Synthesis: Serves as a versatile handle for creating molecular probes to study biological pathways and protein functions.
• Material Science Research: Potential building block for creating functionalized polymers or organic electronic materials with specific optoelectronic properties.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Heterocyclic Chemistry: Fundamental reagent for constructing more complex fused or substituted thiazole-containing heterocyclic systems.

Basic Information

Product Name	2-Bromo-1-Thiazol-5-Yl-Ethanone Hydrobromide
CAS No.	231297-35-1
Molecular Formula	C5H5Br2NOS
Molecular Weight	311.97 g/mol
Synonyms	2-Bromo-1-(thiazol-5-yl)ethanone hydrobromide; 5-Acetylthiazole, 2-bromo-, hydrobromide; 1-(1,3-Thiazol-5-yl)-2-bromoethanone hydrobromide; 2-Bromo-1-(1,3-thiazol-5-yl)ethan-1-one hydrobromide; Ethanone, 2-bromo-1-(5-thiazolyl)-, hydrobromide; Thiazole-5-yl bromomethyl ketone hydrobromide; 5-(2-Bromoacetyl)thiazole hydrobromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Thiazol-5-Yl-Ethanone Hydrobromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.