Description

2-Bromo-4-(1,3-Dioxolan-2-Yl)Thiazole (Wxc08602) is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce functionalized thiazole motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing brominated heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the thiazole ring system is a core pharmacophore.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille).

Basic Information

Product Name	2-Bromo-4-(1,3-Dioxolan-2-Yl)Thiazole (Wxc08602)
CAS No.	231278-12-9
Molecular Formula	C6H6BrNO2S
Molecular Weight	236.09 g/mol
Synonyms	2-Bromo-4-(1,3-dioxolan-2-yl)-1,3-thiazole; 4-(1,3-Dioxolan-2-yl)-2-bromothiazole; Thiazole, 2-bromo-4-(1,3-dioxolan-2-yl)-; WXC-08602; Wxc08602; 2-Bromo-4-(1,3-dioxolan-2-yl)thiazole; 2-Bromo-4-(2,2-dimethyl-1,3-dioxolan-4-yl)thiazole (related protected form)
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(1,3-Dioxolan-2-Yl)Thiazole undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system supports the delivery of material suitable for research and scale-up applications. Certificates of Analysis (COA) detailing purity and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.