Description

tert-Butyl 6,7-Dihydrothieno[3,2-C]Pyridine-5(4H)-Carboxylate is a high-value pharmaceutical intermediate and versatile chemical building block. Its core value lies in its role as a key precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular systems. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and fine chemical industries who require a reliable, high-purity scaffold for constructing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of clopidogrel and other thienopyridine-class antiplatelet agents.
• API Synthesis: Serves as a key building block for the development of novel Active Pharmaceutical Ingredients (APIs) targeting P2Y12 receptors.
• Medicinal Chemistry Research: Used in R&D for constructing and screening new chemical entities with potential therapeutic activity.
• Process Chemistry: Employed in route scouting and scale-up optimization for the commercial production of thienopyridine derivatives.
• Fine Chemical Synthesis: Acts as a versatile scaffold for synthesizing more complex heterocyclic compounds in custom synthesis projects.

Basic Information

Product Name	tert-Butyl 6,7-Dihydrothieno[3,2-C]Pyridine-5(4H)-Carboxylate
CAS No.	230301-73-2
Molecular Formula	C12H17NO2S
Molecular Weight	239.34 g/mol
Synonyms	tert-Butyl 4,5,6,7-tetrahydrothieno[3,2-c]pyridine-5-carboxylate; 5-tert-Butoxycarbonyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; 5-Boc-4,7-dihydro-5H-thieno[3,2-c]pyridine; Clopidogrel Intermediate; BOC-Thienopyridine; TBTPC; 230301-73-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 6,7-Dihydrothieno[3,2-C]Pyridine-5(4H)-Carboxylate is manufactured under strict quality management systems. We provide material that meets stringent in-house specifications, with typical purity levels exceeding 98.0% (by HPLC). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure compliance with your R&D or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.