Description

1H-Indole-2-Carboxylic Acid, 4-Chloro-, Methyl Ester is a high-purity, synthetically valuable indole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a functionalized indole scaffold essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Organic Synthesis Building Block: Employed in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its reactive ester and halogenated indole functionalities.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Biochemical Probe Development: Utilized in creating labeled compounds or inhibitors for studying enzymatic pathways and biological mechanisms.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 4-Chloro-, Methyl Ester
CAS No.	230291-43-7
Molecular Formula	C10H8ClNO2
Molecular Weight	209.63 g/mol
Synonyms	4-Chloro-1H-indole-2-carboxylic acid methyl ester; Methyl 4-chloro-1H-indole-2-carboxylate; 4-Chloroindole-2-carboxylic acid methyl ester; 1H-Indole-2-carboxylic acid, 4-chloro-, methyl ester; 230291-43-7; Methyl 4-chloroindole-2-carboxylate; 4-Chloro-2-(methoxycarbonyl)indole
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylic Acid, 4-Chloro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.