Description

3-Chloro-4-Methyl-2-Thiophenecarboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of conductive polymers, organic semiconductors, and advanced organic frameworks.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the creation of specialized chemical libraries.
• Ligand Synthesis: Useful for constructing complex chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	3-Chloro-4-Methyl-2-Thiophenecarboxylic Acid
CAS No.	229342-86-3
Molecular Formula	C7H5ClO2S
Molecular Weight	188.63 g/mol
Synonyms	3-Chloro-4-methylthiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 3-chloro-4-methyl-; 3-Chloro-4-methyl-2-carboxythiophene; 3-Chloro-4-methylthiophene-2-carboxylic acid; 229342-86-3; 3-Chloro-4-methyl-2-thiophenecarboxylic acid; 4-Methyl-3-chlorothiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Methyl-2-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates to support our global clientele's regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.