Description

3-Butyn-2-Ol,4-(4-Fluorophenyl)-,(2S)-(9Ci) is a chiral, fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research and development chemists and process development teams in pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the fluorophenyl moiety for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of advanced organic materials and liquid crystals due to its rigid, conjugated structure.
• Academic & Contract Research: A valuable tool for methodological studies in organic chemistry, particularly in Sonogashira coupling and other alkyne-based reactions.

Basic Information

Product Name	3-Butyn-2-Ol,4-(4-Fluorophenyl)-,(2S)-(9Ci)
CAS No.	229015-35-4
Molecular Formula	C₁₀H₉FO
Molecular Weight	164.18 g/mol
Synonyms	(2S)-4-(4-Fluorophenyl)-3-butyn-2-ol; (S)-4-(4-Fluorophenyl)-3-butyn-2-ol; (S)-1-(4-Fluorophenyl)-3-butyn-2-ol; 4-(4-Fluorophenyl)-3-butyn-2-ol, (S)-; 229015-35-4; (2S)-1-(4-Fluorophenyl)-3-butyn-2-ol; (S)-4-(p-Fluorophenyl)-3-butyn-2-ol
EINECS	Contact for details

Quality Control

Our 3-Butyn-2-Ol,4-(4-Fluorophenyl)-,(2S)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.