Description

2-Boc-7-Iodo-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is a high-value, protected amino acid derivative and a key synthetic intermediate in advanced organic chemistry. Its primary value lies in its dual functionality, featuring a carboxylic acid group and a Boc-protected amine on a tetrahydroisoquinoline scaffold, which is crucial for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex drug candidates, particularly those targeting neurological disorders and cancer.
• Peptidomimetics Research: Used to incorporate constrained, non-natural amino acid motifs into peptide chains to enhance stability and biological activity.
• Combinatorial Chemistry: Serves as a versatile scaffold in the generation of diverse compound libraries for high-throughput screening.
• Agrochemical Synthesis: Employed in the development of advanced herbicides and pesticides with novel modes of action.
• Chemical Biology Probes: Utilized to create labeled or tagged molecules for studying biological pathways and protein interactions.
• Academic & R&D: A fundamental reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Item	Details
Product Name	2-Boc-7-Iodo-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
CAS No.	228728-16-3
Molecular Formula	C15H18INO4
Molecular Weight	403.22 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-7-iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 7-Iodo-2-[(tert-butoxycarbonyl)amino]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 2-Boc-amino-7-iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 2-(tert-Butoxycarbonylamino)-7-iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 7-Iodo-2-Boc-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 2-Boc-7-Iodo-Tic-OH; Boc-7-Iodo-Tic-OH
EINECS	Contact for details

Quality Control

Our 2-Boc-7-Iodo-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity suitable for sensitive research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to prevent decomposition. Keep the container sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.