Description

7-Iodo-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is a high-value, halogenated tetrahydroisoquinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a carboxylic acid and an iodine substituent, makes it a versatile building block for constructing complex molecular architectures. This compound is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other specialized organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Sonogashira) and other transformations to introduce the tetrahydroisoquinoline scaffold into more complex molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and herbicides.
• Material Science: Can be investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	7-Iodo-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
CAS No.	228728-13-0
Molecular Formula	C10H10INO2
Molecular Weight	303.10 g/mol
Synonyms	7-Iodo-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 7-Iodo-3,4-dihydro-1H-isoquinoline-3-carboxylic acid; 7-Iodotetrahydroisoquinoline-3-carboxylic Acid; 228728-13-0; 7-Iodo-THIQ-3-COOH; 7-Iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 3-Carboxy-7-iodo-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 7-Iodo-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.