Description

6-Amino-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for synthesizing complex molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and potential drug candidates.
• Neurological Research: Used in the development of molecules targeting neurological receptors and pathways due to its isoquinoline scaffold.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Employed in multi-step synthetic routes for the production of investigational new drugs (INDs).
• Chemical Biology: Useful for creating probes and tool compounds to study biological mechanisms.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	6-Amino-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride
CAS No.	228728-09-4
Molecular Formula	C10H13N2O2·HCl
Molecular Weight	228.68 g/mol
Synonyms	6-Amino-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride; 3-Isoquinolinecarboxylic acid, 6-amino-1,2,3,4-tetrahydro-, hydrochloride (1:1); 6-Amino-TIQ-3-COOH·HCl; ATIQCA hydrochloride; 6-Amino-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid HCl salt
EINECS	Contact for details

Quality Control

Our 6-Amino-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.