Description

2,4-Dinitrofluorobenzene-D3 is a deuterated isotopologue of the classic Sanger's reagent, where three hydrogen atoms are replaced by deuterium. This labeled compound is essential for applications requiring precise tracking and quantification, offering enhanced stability and specificity in analytical methods. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, derivatization agent, or tracer in mass spectrometry and NMR studies.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical internal standard in LC-MS and GC-MS for the accurate quantification of its non-deuterated counterpart or related compounds.
• Biomolecule Derivatization & Labeling: Used in proteomics and peptide sequencing to label and identify amino acids, particularly N-terminal amino groups, leveraging the isotopic label for differentiation.
• Metabolic Pathway Tracing: Acts as a stable isotopic tracer in metabolic studies within pharmaceutical and biochemical research.
• Chemical Synthesis Intermediate: Employed as a specialized building block in the synthesis of deuterated fine chemicals and active pharmaceutical ingredients (APIs).
• Analytical Method Development: Crucial for developing and validating sensitive analytical methods that require isotopic dilution techniques.
• Quality Control & Reference Material: Functions as a certified reference material (CRM) in high-purity analytical laboratories.

Basic Information

Product Name	2,4-Dinitrofluorobenzene-D3
CAS No.	228719-18-4
Molecular Formula	C6H2D3FN2O4
Molecular Weight	189.12 g/mol
Synonyms	1-Fluoro-2,4-dinitrobenzene-D3; D3-Sanger's Reagent; DFDNB-D3; 2,4-DNFB-D3; (2,4-Dinitrophenyl)-D3 fluoride; 1,3-Dinitro-4-fluorobenzene-D3; F-DNB-D3; D3-2,4-Dinitrofluorobenzene
EINECS	Contact for details

Quality Control

Our 2,4-Dinitrofluorobenzene-D3 is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D%, typically >98 atom % D), chemical purity, and identity is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.