Description

1-[2-(3-Fluoro-4-Methylphenyl)-1,3-Thiazol-4-Yl]Ethan-1-One is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecules with tailored biological and material properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom and thiazole moiety enhance bioactivity and environmental stability.
• Material Science Research: Employed as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated structure.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags or molecular probes to study biological processes and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the scale-up and production of proprietary compounds.

Basic Information

Product Name	1-[2-(3-Fluoro-4-Methylphenyl)-1,3-Thiazol-4-Yl]Ethan-1-One
CAS No.	228581-94-0
Molecular Formula	C12H10FNO1S
Molecular Weight	235.28 g/mol
Synonyms	1-[2-(3-Fluoro-4-methylphenyl)-1,3-thiazol-4-yl]ethanone; 2-(3-Fluoro-4-methylphenyl)-4-acetylthiazole; 4-Acetyl-2-(3-fluoro-4-methylphenyl)thiazole; 1-(2-(3-Fluoro-4-methylphenyl)thiazol-4-yl)ethan-1-one; 228581-94-0; AKOS BRN 0979; 3-Fluoro-4-methyl-2-thiazolyl phenyl ketone
EINECS	Contact for details

Quality Control

Our 1-[2-(3-Fluoro-4-Methylphenyl)-1,3-Thiazol-4-Yl]Ethan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.