Description

Tropine-3-Thiol is a specialized organosulfur compound derived from the tropane alkaloid skeleton, serving as a key chiral intermediate and building block in advanced organic synthesis. Its unique structure, featuring both a tertiary amine and a thiol group, makes it a versatile precursor for the development of pharmacologically active molecules and complex ligands. This compound is particularly valuable for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce sulfur-containing moieties with high stereochemical control.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, particularly in the development of central nervous system (CNS) agents and anticholinergic compounds.
• Chiral Ligand Synthesis: Used in the preparation of sophisticated chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides, leveraging its bioactive tropane core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and receptor interactions due to its reactive thiol group.
• Fine Chemical Manufacturing: Utilized in custom synthesis and contract manufacturing for producing high-value, complex specialty chemicals.

Basic Information

Product Name	Tropine-3-Thiol
CAS No.	228573-90-8
Molecular Formula	C8H15NOS
Molecular Weight	173.27 g/mol
Synonyms	3-Thiotropine; 8-Methyl-8-azabicyclo[3.2.1]octane-3-thiol; Tropan-3-thiol; 3-Mercaptotropane; 8-Azabicyclo[3.2.1]octane-3-thiol, 8-methyl-; Tropine thiol; 3-Thioltropane
EINECS	Contact for details

Quality Control

Our Tropine-3-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.