Description

2-Amino-4-(Trifluoromethyl)Thiophenol is a high-value, multi-functional aromatic building block characterized by its unique combination of an amino group, a thiol group, and a trifluoromethyl substituent. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts desirable properties like metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocycles and functionalized ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the CF₃ group enhances biological activity.
• Ligand Precursor: Serves as a starting material for synthesizing specialized ligands in catalysis and material science.
• Heterocyclic Chemistry: Integral for constructing sulfur and nitrogen-containing heterocycles like benzothiazoles and thiazoles.
• Material Science: Potential monomer or modifier for advanced polymers and functional surfaces.
• Chemical Research: A versatile reagent for exploring new synthetic methodologies and fluorinated compound libraries.

Basic Information

Product Name	2-Amino-4-(Trifluoromethyl)Thiophenol
CAS No.	228401-48-7
Molecular Formula	C₇H₆F₃NS
Molecular Weight	193.19 g/mol
Synonyms	2-Amino-α,α,α-trifluoro-p-toluenethiol; 2-Amino-4-(trifluoromethyl)benzenethiol; 4-(Trifluoromethyl)-2-aminobenzenethiol; 2-Mercapto-5-(trifluoromethyl)aniline; Benzenethiol, 2-amino-4-(trifluoromethyl)-; 2-Amino-4-trifluoromethylthiophenol
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-(Trifluoromethyl)Thiophenol is produced under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and commercial use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, minimize exposure to air and moisture during handling.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.